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主营:基因诊断
℡ 4000-520-616
℡ 4000-520-616
Enzolifesciences/Neurofilament M monoclonal antibody (3H11)/ADI-NBA-140-E/100µl
产品编号:ADI-NBA-140-E
市  场 价:¥5720.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$286.00
品      牌: Enzo Life
公      司:Enzolifesciences,Inc.
公司分类:
Enzolifesciences/Neurofilament M monoclonal antibody (3H11)/ADI-NBA-140-E/100µl
商品介绍

Product Specification:

Alternative Name:NEFM, NF-M
 
Clone:3H11
 
Host:Mouse
 
Isotype:IgG1
 
Immunogen:Recombinant rat neurofilament M (NF-M) (C-terminal fragment).
 
UniProt ID:P12839
 
Species reactivity:Human, Mouse, Rat
Chicken
 
Applications:ICC, WB
 
Recommended Dilutions/Conditions:Immunocytochemistry (1:25-1:100)
Western Blot (1:200-1:1,000 ECL)
Suggested dilutions/conditions may not be available for all applications.
Optimal conditions must be determined individually for each application.
 
Purity Detail:Protein A affinity purified.
 
Formulation:Liquid. In PBS containing 50% glycerol, 0.01% thimerosal, and 1.0mg/ml BSA.
 
Shipping:Shipped on Blue Ice
 
Long Term Storage:-20°C
 
Scientific Background:Neuron-specific neurofilaments belong to the intermediate filament protein family, also known as 10nm filaments. As major constituents of the axonal cytoskeleton, neurofilaments contain heteropolymers of three major proteins: 200 kDa heavy molecular weight protein NF-H, 160 kDa medium molecular weight protein NF-M, and 68 kDa light molecular weight protein NF-L, with the ratio of each changing during neuronal development. All three proteins contain globular head and tail domains flanking a central alpha-helical domain. An accumulation of neurofilament proteins and/or mutations in one of the three major proteins occur during the progression of numerous neurological diseases, including ALS.
 
品牌介绍
Enzo Biochem是分子诊断领域的先驱,通过开发独特的诊断平台技术来引领临床实验室,生命科学和知识产权的融合,该技术提供了许多超越先前标准的优势。恩佐(Enzo)是一家全球性公司,利用跨职能团队开发和部署产品系统和服务,以满足当今和未来不断变化和快速增长的医疗保健需求。Enzo产品和技术的基础是广泛而深入的知识产权产品组合,其专利涵盖了许多关键的启用技术。恩佐(Enzo)在操纵和修改遗传材料和其他生物分子方面拥有专有技术和专业知识。
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