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主营:基因诊断
℡ 4000-520-616
℡ 4000-520-616
Enzolifesciences/Orexin receptor 2 polyclonal antibody/BML-SA647-0200/200µl
产品编号:BML-SA647-0200
市  场 价:¥10580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$529.00
品      牌: Enzo Life
公      司:Enzolifesciences,Inc.
公司分类:
Enzolifesciences/Orexin receptor 2 polyclonal antibody/BML-SA647-0200/200µl
商品介绍

ProductSpecification:

AlternativeName:OX2R
 
Host:Rabbit
 
Immunogen:Syntheticpeptidecorrespondingtoaa391-405ofratOX2R(orexinreceptor2).
 
UniProtID:P56719
 
Speciesreactivity:Human,Mouse,Rat
 
Applications:ICC,IHC,WB
 
Shipping:ShippedonBlueIce
 
LongTermStorage:-20°C
 
ScientificBackground:OX2RisoneoftworeceptorsthatrecognizethepeptideneurotransmittersorexinAandorexinB1.OrexinAandBare33and28aminoacidsinlength,respectively,andarederivedfromacommonprecursor,prepro-orexin.OX1RbindsorexinAwithten-foldgreateraffinitythantoorexinB.OX2Rbindsbothligandswithsimilaraffinities2,3.BothOX1RandOX2Rbelongtothe7-transmembranedomain,Gprotein-coupledreceptor(GPCR)superfamily.OX2RisthoughttotransmitsignalsthroughtheGa11classofGproteins,resultingintheactivationofphospholipaseCwithsubsequenttriggeringofthephosphatidylinositolcascadeandaninfluxofextracellularCa2+,probablythroughtransientreceptorpotential(TRP)channels2,3.TheorexinsystemhasbeenshowntobeinvolvedintheregulationofsleepandwakefulnessstatesandOX1RknockoutmiceshowdefectsintheregulationofREMsleep,amongotherphenotypicalterations4.Inaddition,theorexinsystemisinvolvedinregulatingautonomicfunctionssuchasbloodpressureandheartrate,aswellasinmechanismsthatregulatetherewardresponseinthebrain4.OX2Risexpressedinboththecentralnervoussystemandperipherallocationssuchasgastrointestinaltissues,pancreas,andtestis.2.
 
品牌介绍
Enzo Biochem是分子诊断领域的先驱,通过开发独特的诊断平台技术来引领临床实验室,生命科学和知识产权的融合,该技术提供了许多超越先前标准的优势。恩佐(Enzo)是一家全球性公司,利用跨职能团队开发和部署产品系统和服务,以满足当今和未来不断变化和快速增长的医疗保健需求。Enzo产品和技术的基础是广泛而深入的知识产权产品组合,其专利涵盖了许多关键的启用技术。恩佐(Enzo)在操纵和修改遗传材料和其他生物分子方面拥有专有技术和专业知识。
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