Enzolifesciences/PDI monoclonal antibody (1D3) (PE conjugate)/ADI-SPA-891PE-F/200µg,Enzo Life,,Enzo Life Sciences,enzolifesciences,Enzo ,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Enzolifesciences/PDI monoclonal antibody (1D3) (PE conjugate)/ADI-SPA-891PE-F/200µg

产品编号：ADI-SPA-891PE-F

市场价：¥10160.00

场地：美国(厂家直采)

产品分类：分子类>其他分子产品>外泌体研究>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$508.00

品牌： Enzo Life

公司：Enzolifesciences,Inc.

公司分类：

商品介绍

Product Specification:

Alternative Name:	P4HB, protein disulfide isomerase

Clone:	1D3

Host:	Mouse

Isotype:	IgG1

Immunogen:	Synthetic peptide corresponding to the sequence near the C-terminus of rat PDI.

UniProt ID:	P04785

Species reactivity:	Human, Mouse, Rat Bovine, Chicken, Dog, Guinea pig, Hamster, Monkey, Porcine, Rabbit, Sheep, Xenopus

Applications:	Flow Cytometry

Recommended Dilutions/Conditions:	Flow Cytometry (1:100) Suggested dilutions/conditions may not be available for all applications. Optimal conditions must be determined individually for each application.

Application Notes:	Detects a band of ~58kDa by Western blot.

Purity Detail:	Protein G affinity purified.

Formulation:	Liquid. In PBS, pH 7.2, containing 0.09% sodium azide.

Handling:	Avoid freeze/thaw cycles. Protect from light.

Shipping:	Blue Ice Not Frozen

Long Term Storage:	+4°C

Scientific Background:	The mammalian protein disulphide-isomerase (PDI) family encompasses several highly divergent proteins involved in the processing and maturation of secretory proteins in the ER by catalyzing the rearrangement of disulphide bonds. PDI, an abundant protein of the ER (>400uM), contains a carboxy-terminal retention signal sequence, KDEL, similar to that of BiP and Grp94. The PDI proteins are characterized by the presence of one or more domains of ~95-110 amino acids related to the cytoplasmic protein thioredoxin. All but the PDI-D subfamily are composed entirely of repeats of such domains, with at least one domain containing - and one domain lacking - a redox-active-Cys-X-X-Cys-tetrapeptide. In addition to roles as redox catalysts and isomerases, PDI proteins perform such functions as peptide binding and cell adhesion, and may conduct chaperone activities. Platelet surface thiols and disulphides play an important role in platelet responses. Catalytically active PDI resides on platelet surfaces where it mediates platelet aggregation and secretion by reducing disulfide bonds, thus exposing fibrinogen receptors in platelets.

品牌介绍

Enzo Biochem是分子诊断领域的先驱，通过开发独特的诊断平台技术来引领临床实验室，生命科学和知识产权的融合，该技术提供了许多超越先前标准的优势。恩佐（Enzo）是一家全球性公司，利用跨职能团队开发和部署产品系统和服务，以满足当今和未来不断变化和快速增长的医疗保健需求。Enzo产品和技术的基础是广泛而深入的知识产权产品组合，其专利涵盖了许多关键的启用技术。恩佐（Enzo）在操纵和修改遗传材料和其他生物分子方面拥有专有技术和专业知识。

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